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Yunjie Xu (Research Professor)

Research interest

Tumor-targeted therapy

Contact
office
Asan Sci. 123A
E-mail
xuyunjie87 at 163.com
Publications
  • Park, M.; Sunwoo, K.; Kim, Y-J.; Won, M.; Xu, Y.; Kim, J.; Pu, Z.; Li, M.; Kim, J. Y.; Seo, J. H.; Kim, J. S. Cutting Off H+ Leaks on Inner Mitochondrial Membrane: A Proton Modulation Approach to Selectively Eradicate Cancer Stem Cells. J. Am. Chem. Soc. 2023, in press.
  • Xiong, H.; Xu, Y.; Kim, B.; Rha, H.; Zhang, B.; Li, M.; Yang, G-F.; Kim, J. S. Photo-Controllable Biochemistry: Exploiting Photocages in the Phototherapeutic Window. Chem 2023, 9, 29-64.
  • Li, M.; Xu, Y.; Peng, X.; Kim, J. S. From Low to No O2-Dependent Hypoxia Photodynamic Therapy (hPDT): A New Perspective. Acc. Chem. Res. 2022, 55, 3253-3264.
    • MORE VIEW
    • Xu, Y.; Xiong, H.; Zhang, B.; Lee, I.; Xie, J.; Li, M.; Zhang, H.; Kim, J. S., Photodynamic Alzheimer’s disease therapy: From molecular catalysis to photo-nanomedicine. Coordin. Chem. Rev. 2022, 470, 214726.
    • Li, C.; Guan, X.; Zhang, X.; Zhou, D.; Son, S.; Xu, Y.; Deng, M.; Guo, Z.; Sun, Y.; Kim, J. S., NIR-II bioimaging of small molecule fluorophores: From basic research to clinical applications. Biosensors and Bioelectronics., 2022, 216, 114620.
    • Li, M.; Xu, Y., Pu, Z., Xiong, T., Huang, H., Long, S., Son, S., Yu, L., Singh, N., Tong, Y., Sessler, J. L., Peng, X., Kim, J. S., Photoredox catalysis may be a general mechanism of photodynamic therapy. Proc. Natl. Acad. Sci. U.S.A. 2022, 119, e2210504119.
    • Yu, L.; Xu, Y.; Pu, Z.; Kang, H.; Li, M.; Sessler, J. L.; Kim, J. S., Photocatalytic Superoxide Radical Generator that Induces Pyroptosis in Cancer Cells. J. Am. Chem. Soc. 2022, 144, 11326-11337.
    • Y. Xu, Y. Wang, J. An, A. C. Sedgwick, M. Li, J. Xie, W. Hu, J. Kang, S. Sen, A. Steinbrueck, B. Zhang, L. Qiao, S. Wageh, J. F. Arambula, L. Liu, H. Zhang, J. L. Sessler, J. S. Kim, ‘2D-Ultrathin MXene/DOXjade Platform for Iron Chelation Chemo-photothermal Therapy’ Bioact. Mater. 76-85, 14, 2022.
    • J. Xie, Y. Wang, W. Choi, P. Jangili, Y. Ge, Y. Xu, J. Kang, L. Liu, B. Zhang, Z. Xie, J. He, N. Xie, G. Nie, H. Zhang, J. S. Kim, ‘Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies’ Chem. Soc. Rev. 9152-9201, 50, 2021.
    • Piao J, Liu S, Xu Y, et al. ‘Ezrin protein overexpression predicts the poor prognosis of pancreatic ductal adenocarcinomas’ Exp. Mol. Pathol., 98(1), 1-6, 2015.
    • Qu X, Sheng J, Shen L, Su J, Xu Y, Xie Q, Wu Y, Zhang X, Sun L. ‘Autophagy inhibitor chloroquine increases sensitivity to cisplatin in QBC939 cholangiocarcinoma cells by mitochondrial ROS’ Plos one, 16, 12(3), 2017.
    • Jin A, Xu Y, Liu S, Jin T, Li Z, Jin H, Lin L, Lin Z, ‘Sineoculis homeobox homolog 1 protein overexpression as an independent biomarker for pancreatic ductal adenocarcinoma’ Exp. Mol. Pathol., 96(1), 54-60, 2014.
    • Yunjie Xu, Weinan Gao, Yong Zhang et al, ‘ABT737 reverses cisplatin resistance via targeting glucose metabolism of human ovarian cancer cells’ Int. J. Oncol., 53(3), 1055-1068, 2018.

Snehasish Debnath (Research Professor)

Research interest

Neuro-degenerative Disease, PDT, Drug delivery system, Bioorthogonal Chemistry

Contact
office
Asan Sci. 548B
E-mail
snehasish14 at gmail.com
Publications
  • J. Kim, Y. Lee, Y. Kim, H. Rha, D. Kim, S. Debnath*, K. Pu*, H. Kang*, J. S. Kim*, ‘Site-specific transformable nanostructures for cancer therapy and diagnosis’ Chem. Rev. 2025 (in press).
  • C. Wang, F. Yuan, C. Fu, Y. Li, G. Dai, H. S. Kim, S. Xia, L. Yu, S. Debnath, W. X. Ren*, J. Shu*, M. Qiu*, J. S. Kim*, ‘High Entropy 2D Layered Double Hydroxides Nanosheet Toward Unprecedented Cascaded Nanozyme-Initiated Chemodynamic and Immune Synergistic Therapy’ J. Am. Chem. Soc. 2025, 147, 136-148.
    • MORE VIEW
    • 6. S. Mondal, J. An, T. Bera, M. Banerjee, S. Debnath, D. Mandal, A. Sikder, S. Guha*, J. S. Kim* and N. D. Pradeep*, “Engineering a GFP-core-inspired NIR-photocage: Exploring meso-GFP-PRPG towards Alzheimer\'s Disease therapeutics”, ACS. Cent. Sci., 2025, 11, 1062-1070.
    • J. An, K. P. Lv, C. V. Chau, J. H. Lim, R. Parida, X. Huang, S. Debnath, Y. Xu, S. Zheng, A. C. Sedgwick, J. Y. Lee, D. Luo*, Q. Liu*, J. L. Sessler*, and J. S. Kim*, “Lutetium texaphyrin-celecoxib conjugate as a potential immuno-photodynamic therapy agent”, J. Am. Chem. Soc. 2024, 146, 28, 19434-19448.
    • Zhang, B. Guo, Y. Jiang, C. Hu, J. Kim, S. Debnath, X. Shi, C. Zhang, J. S. Kim*, and F. Wang*, “Luciferase-decorated gold nanorods as dual-modal contrast agents for tumor-targeted high-performance bioluminescence/photoacoustic imaging”, Anal. Chem. 2024, 96, 9132-9140.
    • S. Debnath, S. S. Paramasivam, D. Pradhan, P. Manickam and P. B. Chatterjee, “A redox-active copper complex for orthogonal detection of homocysteine involving fluorescence and electrochemical techniques”, Small 2025, 21, 2409982.
    • R. Ghosh, D. Pradhan, S. Debnath, A. Mansingh, N. Nagesh, and P. B. Chatterjee, “A hydrogen-bonded non-porous organic inorganic framework for measuring cysteine in blood plasma and endogenous cancer cell”, Chem. Eur. J. 2024, 30, e202401255.
    • R. Ghosh, R. R. Nair, S. Ghosh, S. Debnath, and P. B. Chatterjee, “A water-soluble wavy coordination polymer of Cu (II) as a turn-on luminescent probe for histidine and histidine-rich proteins/peptides”, Inorg. Chem. 2024, 63, 8320-8328.
    • R. Ghosh, S. Luhar, S. Debnath, K. B. Patel, K. Baskaran, D. N. Srivastava and P. B. Chatterjee, “Measurement of the malignancy marker spermine in human biofluids using smartphone readout and impedance techniques: Analytical validation using HPLC”, Sens. Actuat B. Chem. 2024, 406, 135390.
    • R. R. Nair, S. Debnath, R. Ghosh, A. Bhattacharya, M. Raju, and P. B. Chatterjee, “Label-free detection of unbound bilirubin and nitrophenol explosives in water by a mechanosynthesized dual functional zinc complex: Recognition of picric acid in various common organic media”, Chem. Eur. J., 2024, 30, e202303068.
    • S. Debnath, R. Ghosh, Pragti, S. Mukhopadhyay, K. Baskaran and P. B. Chatterjee, “Fabrication of paper-based facile and low-cost microfluidic device and digital imaging technique for point-of-need monitoring of hypochlorite”, Analyst, 2023, 148, 4072-4083.
    • S. Debnath, S. V. Navadiya, R. Ghosh, D. Pradhan and P. B. Chatterjee, “Coumarin-ensembled vanadium(V) compounds and their affinity studies toward biological thiols probed by fluorescence spectroscopy”, Chem. Asian J., 2023, 18, 202201162.
    • S. Debnath, R. Ghosh, R. R. Nair, D. Pradhan and P. B. Chatterjee, “Advances in the development of water-soluble fluorogenic probes for bioimaging of hypochlorite/hypochlorous acid in cells and organisms”, ACS Omega, 2022, 43, 38122-38149.
    • S. Debnath, R. R. Nair, R. Ghosh, K. Gaddam, N. Radhakishan, N. Nagesh and P. B. Chatterjee, “A unique water soluble probe for measuring the cardiac marker homocysteine and its clinical validation” Chem. Commun., 2022, 58, 9210-9213.
    • S. Debnath, and P. B. Chatterjee, “Enantiopure chiroptical probes for circular dichroism and absorbance based detection of nerve gas simulants” Chem. Commun., 2022, 58, 9006-9009.
    • S. Debnath, R. R. Nair, R. Ghosh, A. Bhattacharya, and P. B. Chatterjee, “Smartphone assisted chromogenic sensing of halogenated solvents and monoaromatic hydrocarbons” Dyes Pigm. 2021, 196, 109821.
    • S. N. Bhaduri, D. Ghosh, S. Debnath, R. Biswas, P. B. Chatterjee, and P. Biswas, “Copper(II)-incorporated porphyrin based porous organic polymer for a nonenzymatic electrochemical glucose sensor’, Inorg. Chem. 2023, 62, 4316-4146.
    • R. Ghosh, S. Debnath, A. Bhattacharya, and P. B. Chatterjee, “Affinity studies of hemicyanine derived water soluble colorimetric probes with reactive oxygen/nitrogen/sulfur species”, ChemBioChem. 2023, 24, 202200541.
    • A. Bhattacharya, R. Ghosh, S. Debnath and P. B. Chatterjee, “A simple, selective, and rapid detection-cum-precipitation of hazardous gold nanoparticles and their discrimination from gold(III) in environmental samples by a chromofluorogenic probe”, Sens. Actuat B. Chem. 2023, 378, 133158.
    • R. Ghosh, S. Debnath, A. Bhattacharya, D. Pradhan and P. B. Chatterjee, “Studies on the interaction between oxido/dioxidovanadium (V) compounds and reactive oxygen species: Synthesis, characterization, and photophysical investigation” J. Inorg. Biochem., 2022, 233, 111845.
    • R. R. Nair, M. Raju, S. Debnath, R. Ghosh and P. B. Chatterjee, “Concurrent detection and treatment of cyanide-contaminated water using mechanosynthesized receptors” Analyst. 2020, 145, 5647-5656.
    • R. R. Nair, S. Debnath, S. Das, P. Wakchaure, B. Ganguly and P. B. Chatterjee, “A highly selective turn-on biosensor for measuring spermine/spermidine in human urine and blood” ACS Appl. Bio Mater. 2019, 2, 2374-2387.
    • M. Raju, R. R. Nair, S. Debnath,and P. B. Chatterjee, “Affinity directed surface functionalization of two different metal nanoparticles by a natural ionophore: probing and removal of Hg2+ and Al3+ ions from aqueous solutions” Inorg. Chem. 2019, 58, 1674-1683.

이민구 (Min-Goo Lee) (Research Professor)

Research interest

Protein Degradation, Regulation of Tumor stress

Contact
office
Asan Sci. 123A
E-mail
mglee @ korea.ac.kr
Publications
  • M.-G. Lee, Z. Choi, N.-J. Lim, J.-S. Lim, K.-W. Lee, K.-P. Ko, B.-K. Ryu, S.-H. Kang, S.-G. Chi*‎, ‘XAF1 directs glioma response to temozolomide through apoptotic transition of autophagy by activation of ATM–AMPK signaling’ Neurooncol Adv. 2022, 4, 1, vdac013. Read here
  • S. Koo, M.-G. Lee, A. Sharma, M. Li, X. Zhang, K. Pu*, S.-G. Chi*, J. S. Kim*, ‘Harnessing GLUT1-Targeted Pro-oxidant Ascorbate for Synergistic Phototherapeutics’ Angew. Chem. Int. Ed 2022, 61, 17, e202110832. Read here
    • MORE VIEW
    • A. Sharma, M.-G. Lee, M. Won, S. Koo, J. F. Arambula, J. L. Sessler*, S.-G. Chi*, and J. S. Kim*, ‘Targeting Heterogeneous Tumors Using a Multifunctional Molecular Prodrug’ J. Am. Chem. Soc. 2019, 141, 39, 15611-15618. Read here
    • A. Sharma, M.-G. Lee, H. Shi, M. Won, J. F. Arambula, J. L. Sessler*, J. Y. Lee*, S.-G. Chi*, J. S. Kim*, ‘Overcoming Drug Resistance by Targeting Cancer Bioenergetics with an Activatable Prodrug’ Chem 2018, 4, 10, 2370-2383. Read here
    • M.-G. Lee, S.-I. Jeong, K.-P. Ko, S.-K. Park. B.-K. Ryu, I.-Y. Kim, J.-K. Kim, S.-G. Chi*, ‘RASSF1A Directly Antagonizes RhoA Activity through the Assembly of a Smurf1-M’ Cancer Res. 2016, 76, 7, 1847-1859. Read here
    • M.-G. Lee, J. Han, S.-I. Jeong, N.-G. Her, J.-H. Lee, T.-K. Ha, M.-J. Kang, B.-K. Ryu, S.-G. Chi*, ‘XAF1 directs apoptotic switch of p53 signaling through activation of HIPK2 and ZNF313’ Proc. Natl. Acad. Sci. U.S.A. 2014, 111, 43, 15532-15537. Read here

Rakesh Mengji (Research Professor)

Research interest

Photoresponsive drug delivery system & bio-imaging system

Contact
office
Asan Sci. 337
E-mail
rakesh.iict15 at gmail.com
Publications
  • Q.Ding, M. Li, L. Mei, S. Hua, Z. Li, R. Mengji, R.Chen, H.Liu, G. Kim, M. Jia, B. Wang, C. Yin, Q. Fan, H. Zhou*, W. Hu*, J. Cui*, and J. S. Kim* ‘Immune-Evasive NIR-II Nanoplatforms for Repeatable Photodynamic Therapy\'ACS.JACS.2026, Read here
  • Q. Ding, B. Wang, Z. Zhan, P, Jangili, J. Chen, R. Mengji, H. Rha, Y. Li*, J. Tian*, J. S. Kim*, ‘MitoSiege-Driven Catalase Collapse: A GSH-Responsive, Mitochondria-Targeted COF Prodrug for Amplified Chemodynamic Therapy\' Angew.Chem.Int. 2025, Read here
    • MORE VIEW
    • J. Tian, L. Zhang, ; Y. Qiao, J. Yang, R. Mengji, Y. Lee, S. Hong, Y. Duan, X. Zhou, J. S. Kim*, J. Zhou*, ‘Viscosity-Tuned Mitochondrial Probe for Precision Tumor Theranostics and Apoptosis Imaging’ Anal. Chem. 2025, 97, 28, 15244–15252. Read here
    • R. Mengji, D. Paladugu, B. Saha*, A. Jana*, ‘Single-Photon Deep-Red Light-Triggered Direct Release of an Anticancer Drug: An Investigative Tumor Regression Study on Breast Cancer Spheroidal-Tumor Model’ J. Med. Chem. 2024, 67, 13, 3650–3661. Read here
    • A. K. Singh#, R. Mengji#, A. V. Nair, S. S. Shah, A. Jana*, N. D. P. Singh*, ‘Photoactivable AIEgen-based Lipid-Droplet-Specific Drug Delivery Model for Live Cell Imaging and Two-Photon Light-Triggered Anticancer Drug Delivery’ ACS Appl. Bio Mater. 2023, 6, 4372. Read here
    • P. K. Singh#, R. Mengji#, S. Kumar, A. K. Singh, A. Jana*, S. P. Singh, ‘BODIPY-Based Mitochondrial Targeted NIR-Responsive CO-Releasing Platform for the On-Demand Release of CO to Treat Cancer’ ACS Appl. Bio Mater. 2023, 6, 3778. Read here
    • A. Sikder, R. Mengji, S. Mondal, A. Jana*, N. D. P. Singh*, ‘Spatiotemporal Photo-Release of Hydrogen Sulfide from β-Carboline-Derived Nanoparticles for Therapeutic Applications’ J. Mater. Chem. B 2023, 11, 5131. Read here
    • B. Roy, R. Mengji, S. Roy, B. Pal, A. Jana*, N. D. P. Singh*, ‘NIR-Responsive Lysosomotropic Phototrigger: An ‘AIE + ESIPT’ Active Naphthalene-Based Single-Component Photoresponsive Nanocarrier with Two-Photon Uncaging and Real-Time Monitoring Ability’ ACS Appl. Mater. Interfaces 2022, 14, 4862. Read here
    • Y. Venkatesh#, V. Vangala#, R. Mengji, A. Chaudhuri, S. Bhattacharya, P. K. Datta, R. Banerjee, A. Jana*, A. Anoop*, N. D. P. Singh*, ‘One- and Two-Photon Uncaging of Carbon Monoxide (CO) with Real-Time Monitoring: On-Demand Carbazole-Based Dual CO-Releasing Platform to Test over Single and Combinatorial Approaches for the Efficient Regression of Orthotopic Murine Melanoma In Vivo’ J. Med. Chem. 2022, 65, 1822. Read here
    • A. Paul, R. Mengji, M. Bera, M. Ojha, A. Jana*, N. D. P. Singh*, ‘Mitochondria-Localized In Situ Generation of Rhodamine Photocage with Fluorescence Turn-On Enabling Cancer Cell-Specific Drug Delivery Triggered by Green Light’ Chem. Commun. 2020, 56, 8412. Read here
    • A. Chaudhuri, R. Mengji, Y. Venkatesh, A. Jana*, N. D. P. Singh*, ‘An Improved Tumor-Specific Therapeutic Strategy by the Spatio-Temporally Controlled In Situ Formation of a Cu(II) Complex, Leading to Prompt Cell Apoptosis via Photoactivation of a Prodrug’ Chem. Commun. 2020, 56, 4559. Read here
    • R. Mengji, C. Acharya, V. Vangala, A. Jana*, ‘A Lysosome Specific Near-Infrared Fluorescent Probe for the in vitro Cancer Cell Detection and Non-Invasive in vivo Imaging’ Chem. Commun. 2019, 55, 14182. Read here
    • M. Gangopadhyay, R. Mengji, A. Paul, Y. Venkatesh, V. Vangala, A. Jana*, N. D. P. Singh*, ‘Redox-Responsive Xanthene–Coumarin–Chlorambucil-Based FRET-Guided Theranostics for \'Activatable\' Combination Therapy with Real-Time Monitoring’ Chem. Commun. 2017, 53, 9109. Read here
    • A. Paul, R. Mengji, O. A. Chandy, S. Nandi, M. Bera, A. Jana*, A. Anoop*, N. D. P. Singh*, ‘ESIPT-Induced Fluorescent o-Hydroxycinnamate: Self-Monitoring Phototrigger for Prompt Image-Guided Uncaging of Alcohols’ Org. Biomol. Chem. 2017, 15, 8544. Read here
    • S. Biswas, R. Mengji, S. Barman, V. Vangala, A. Jana*, N. D. P. Singh*, ‘‘AIE + ESIPT’ Assisted Photorelease: Fluorescent Organic Nanoparticles for Dual Anticancer Drug Delivery with Real-Time Monitoring Ability’ Chem. Commun. 2018, 54, 168. Read here

Yuling Xu (Research Professor)

Research interest

Bioimaging, Phototheranostics

Contact
office
Asan Sci. 337
E-mail
xuyuling.chem at gmail.com
Publications
  • Y. Xu, C. Li, J. An, X. Ma, J. Yang, L. Luo, Y. Deng, J. S. Kim, Y. Sun, ‘Construction of a 980 nm laser-activated Pt(II) metallacycle nanosystem for efficient and safe photo-induced bacteria sterilization’ Sci. China. Chem. 2023, 66, 155. Read here
  • Y. Xu, Y. Zhang, J. Li, J. An, C. Li, S. Bai, A. Sharma, G. Deng, J. S. Kim, Y. Sun, ‘NIR-II emissive multifunctional AIEgen with single laser-activated synergistic photodynamic/photothermal therapy of cancers and pathogens’ Biomaterials 2020, 259, 120315. Read here
    • MORE VIEW
    • Y. Xu, C. Li, X. Ma, W. Tuo, L. Tu, X. Li, Y. Sun, P. J. Stang, Y. Sun, ‘Long wavelength–emissive Ru(II) metallacycle-based photosensitizer assisting in vivo bacterial diagnosis and antibacterial treatment’ Proc. Natl. Acad. Sci. USA 2022, 119, e2209904119. Read here
    • Y. Xu, C. Li, S. Lu, Z. Wang, S. Liu, X. Yu, X. Li, Y. Sun, ‘Construction of emissive ruthenium(II) metallacycle over 1000 nm wavelength for in vivo biomedical applications’ Nat. Commun. 2022, 13, 2009. Read here
    • Y. Xu, Y. Pang, L. Luo, A. Sharma, J. Yang, C. Li, S. Liu, J. Zhan, Y. Sun, ‘De Novo Designed Ru(II) Metallacycle as a Microenvironment-Adaptive Sonosensitizer and Sonocatalyst for Multidrug-Resistant Biofilms Eradication’ Angew. Chem. Int. Ed. 2024, 63, e202319966. Read here

Qihang Ding

Research interest

Fabrication of organic small molecule probes in the NIR-II

Contact
office
Asan sci. 238
E-mail
dingqihang at whu.edu.cn
Publications
  • Q. Li, Q. Ding, Y. Li, X. Zeng, Y. Liu, S. Lu, H. Zhou, X. Wang, J.Wu, X. Meng, Z. Denga and Y. Xiao ‘Novel small-molecule fluorophores for in vivo NIR-IIa and NIR-IIb imaging’ Chemical Communications. doi:10.1039/c9cc09865h
  • Y. Li, Y. Liu, Q. Li, X. Zeng, T. Tian, W.Zhou, Y. Cui, X. Wang, X. Cheng, Q. Ding, X. Wang, J. Wu, H. Deng, Y. Li, X. Meng, Z. Deng, X. Honga, and Y. Xiao ‘Novel NIR-II organic fluorophores for bioimaging beyond 1550 nm’ Chemical Science. doi:10.1039/c9sc06567a
  • H. Zhou, W. Yi, A. Li, B. Wang, Q. Ding, L. Xue, X. Zeng, Y. Feng, Q. Li, T. Wang, Y. Li, X. Cheng, L. Tang, Z. Deng, M. Wu, Y. Xiao, and X. Hong ‘Specific Small‐Molecule NIR‐II Fluorescence Imaging of Osteosarcoma and Lung Metastasis’ Advanced Healthcare Materials. doi:10.1002/adhm.201901224
    • MORE VIEW
    • J. Lin, Q. Li, X. Zeng, Z. Chen, Q. Ding, Y. Li, H. Zhou, X. Meng, D. Chen, Z. Deng, X. Hong and Y. Xiao ‘A novel small-molecule near-infrared II fluorescence probe for orthotopic osteosarcoma imaging’ SCIENCE CHINA Chemistry 63, 766 (2020); doi: 10.1007/s11426-019-9685-6

김정륜 (Jungryun Kim)

Research interest

Bioorthogonal Chemistry, Phototherapeutics

Contact
office
Asan Sci. 238
E-mail
ryunnkim at korea.ac.kr
Publications
  • J. Kim†, S. Debnath†, E. Kim, C. Yoon, J. Seo, S. Hua, J. S. Kim*, ‘Tetrazine Mediated Bioorthogonally Activated Therapeutic (TBAT) Platform’ J. Am. Chem. Soc. 2026 (ASAP). Read here

  • J. Kim†, Y. Lee†, Y. Kim†, H. Rha, D. Kim, S. Debnath, K. Pu*, H. Kang*, J. S. Kim*, ‘Site-specific transformable nanostructures for cancer therapy and diagnosis’ Chem. Rev. 2025 125, 9012. Read here

    • MORE VIEW
    • J. Kim†, C. Hu†, P. Jangili, C. Tang*, F. Wang*, J. S. Kim*, ‘Dexamethasone-appended activatable prodrug overcoming multidrug resistance’ J. Med. Chem. 2025, 68, 23589-23597​. Read here

    • J. H. Kim, B. Y. K. Hui, Ji. Lee, K.-w. Lee, J. Kim, Y. Kim, M. H. Chua, J. Xu, M.-G. Lee, X. Liu, J. S. Kim, ‘PET-leveraged ALDH probe toward cancer stem cells’ J. Mat. Chem. B 2025 13, 11809. Read here

    • Q. Ding, J. Liu, Y. Wang, J. Kim, Z. Huang, Y. Lee, H. Zhou, P. Zhang, J. L. Sessler, J. S. Kim, ‘Dual-laser ‘808 and 1064 nm’ strategy that circumvents the Achilles’ heel of photothermal therapy’ PNAS 2025 122, e2503574122. Read here

    • S. Chen†, G. Yuan†, L. Wang†, J. Kim†, H. Wang, J. Yoo, F. Cao, X. Lin, H. Huang, J. S. Kim, H. Xia, P. Zhang, ‘Metalla-Aromatic Oligomers: Efficient Photocatalytic Activation for Phototherapy’ J. Med. Chem. 2025, 68, 11, 11841-11851. Read here

    • J. Gong†, Q. Ding†, Y. Shi, M. Li, C. Liu, W. Zeng, J. Kim, S. Shan, W. Zhang, M. Qi*, J. S. Kim*‎, ‘NIR-responsive gold nanomaterials in photothermal antibacterial therapy: From morphological design to multifunctional platforms’ Coord. Chem. Rev. 2024, 526, 216348. Read here
    • J. Kim†, Y. Xu†*, J. H. Lim†, J. Y. Lee*, M. Li*, J. M. Fox*, M. Vendrell*, J. S. Kim*, ‘Bioorthogonal Activation of Deep Red Photoredox Catalysis Inducing Pyroptosis’ J. Am. Chem. Soc. 2025, 147, 701-712. Read here
    • K. Dou†, J. Lu†, Y. Xing, R. Wang, M. Won, J. Kim, F. Yu*, J. S. Kim*, ‘Metabolic Acidity/H2O2 Dual-Cascade-Activatable Molecular Imaging Platform toward Metastatic Breast Tumor Malignancy’ Angew. Chem. Int. Ed. 2024, e202419191. Read here
    • Y. Xu†, J. Kim, H. Rha, J. S. Kim*, ‘Oxidative photocatalysis on intracellular on intracellular membranes lights up Photopyro’ Matter 2024, 7, 3253-3255. Read here
    • F. Mehvari†, V. Ramezanzade†, J. An, J. Kim, M. Dinari*, J. S. Kim*‎, ‘Biopolymer-based hydrogels for biomedical applications: bioactivity and wound healing properties’ Coord. Chem. Rev. 2024, 518, 216093. Read here
    • B. Zhu†, X. Xing, J. Kim, H. Rha, C. Liu, Q. Zhang, L. Zeng*, M. Lan*, J. S. Kim*, ‘Endogenous CO imaging in bacterial pneumonia with a NIR fluorescent probe’ Biomaterials 2023, 304, 122419. Read here
    • S. Lee, J. Yoo, G. Bae, R. Thangam, J. Heo, J. Y. Park, H. Choi, C. Kim, J. An, J. Kim, K. R. Mun, S. Shin, K. Zhang, P. Zhao, Y. Kim, N. Kang, S.-B. Han, D. Kim, J. Yoon, M. Kang, J. Kim, L. Yang, S. Karamikamkar, J. Kim, Y. Zhu, A. H. Najafabadi, D.-H. Kim, K.-B. Lee, S. J. Oh, H.-C. Song, W. Y. Jang, L. Bian, Z. Chu, J. S. Kim, Y. S. Zhang, Y. Kim, H. S. Jang*, S. Kim*, H. Kang*, ‘Photonic control of ligand nanospacing in self-assembly regulates stem cell fate’ Bioact. Mater., 2024, 34, 164-180. Read here
    • J. Kim†, P. Jangili†*, J. Kim†, S. Lucia, J. Ryu, R. Prasad, S. Zi, P. Kim*, W. Sun*, J. S. Kim*, ‘Mitochondrial NIR imaging probe mitigating oxidative damage by targeting HDAC6’ Chem. Commun. 2023, 59, 10109-10112. Read here
    • Z. Mao†, H. Rha†, J. Kim†, X. You, F. Zhang*, W. Tao*, J. S. Kim*, ‘THQ-Xanthene: An Emerging Strategy to Create Next-Generation NIRI/II Fluorophores’ Adv. Sci. 2023, 10, 2301177. Read here
    • M. Li†, J. Kim†, H. Rha, S. Son, Y. Xu*, J. L. Sessler*, J. S. Kim*, ‘Photon-Controlled Pyroptosis Activation (PhotoPyro): An Emerging Trigger for Antitumor Immune Response’ J. Am. Chem. Soc. 2023, 145, 6007-6023. Read here
    • L. Yu†, Y. Xu, J. Kim, J. Lee, J. S. Kim*, ‘A rational design of AIE-active fluorophore for the fingerprint optical detection’ Bull. Korean Chem. Soc. 2023, 44, 516-522. Read here
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