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김재원 (Jaewon Kim)

Research interest

Organic synthesis & Optical imaging probe

Contact
office
Asan Sci. 337
E-mail
kcjb2929 at gmail.com
Publications
  • Y. Jiang, S. Huang, H. Ma, J. Weng, X. Du, Z. Lin, J. Kim, W. You, H. Zhang, D. Wang, J. S. Kim, ‘RNA-Activatable Near-Infrared Photosensitizer for Cancer Therapy’ J. Am. Chem. Soc., 2024, 146, 36, 25270-25281. Read here

  • J. Kim, J. Yoo, B. Kim, K.-W. Lee, S. Kim, S. Hong, J. S. Kim, ‘An AIE-based fluorescent probe to detect peroxynitrite levels in human serum and its cellular imaging’ Chem. Commun., 2024, 60, 5443-5446. Read here

  • F. Mehvari, V. Ramezanzade, P. Asadi, N. Singh, J. Kim, M. Dinari*, J. S. Kim* ‘A panoramic perspective of recent progress in 2D and 3D covalent organic frameworks for drug delivery’ Aggregate, 2024, e480.
    • J. Xiong, X. Wang J. Kim, J. Gong, Z. Mao*, J. S. Kim*, Z. Liu* ‘Tumor-Activated Prodrug with Synergistic Anti-Stemness Chemical and Photodynamic Therapies’ Adv. Funct. Mater., 2023, 2312590.
    • J. Kim, S. Lee, Y. Kim, M. Choi, I. Lee, E. Kim, C. G. Yoon, K. Pu*, H. Kang*, J. S. Kim* ‘In situ self-assembly for cancer therapy and imaging’ Nat. Rev. Mater., 2023, 8, 710-725.
    • Z. Liu, Z. Han, X. Jin, J. An, J. Kim, W. Chen, J. S. Kim*, J. Zheng*, J. Deng*, ‘Regulating the microenvironment with nanomaterials: Potential strategies to ameliorate COVID-19’ Acta Pharm. Sin. B., 2023, 13(9), 3638-3658.
    • M. Park, K. Sunwoo, Y.-J. Kim, M. Won, Y. Xu, J. Kim, Z. Pu, M. Li*, J. Y. Kim*, J. H. Seo*, J. S. Kim*, ‘Cutting Off H+ Leaks on Inner Mitochondrial Membrane: A Proton Modulation Approach to Selectively Eradicate Cancer Stem Cells.’ J. Am. Chem. Soc., 2023, 8, 4647-4658.
    • N.Singh, J. Kim, J. Kim, K. Lee, Z. Zunbul, I. Lee, S. G. Chi*, J. S. Kim*, ‘Covalent organic framework nanomedicines: Biocompatibility for advanced nanocarriers and cancer theranostics applications’ Bioact. Mater., 2023, 21, 358-380.
    • S. Son, J. Kim, J. Kim, B. Kim, J. Lee, Y. Kim, M. Li*, H. Kang*, J. S. Kim*, ‘Cancer therapeutics based on diverse energy sources’ Chem. Soc. Rev., 2022, 51, 8201-8215.
    • J. Kim, S. Lee, M. S. Han*, ‘pH-guided fluorescent sensing probe for the discriminative detection of Cl and Br in human serum’ Anal. Chim. Acta, 2022, 1210, 339879.
    • L.-X. Huang, Y.-B. He, J. Kim, A. Sharma, Q.-Y. Cao*, J. S. Kim*, ‘Pyridinium-conjugated polynorbornenes for nanomolar ATP sensing using an indicator displacement assay and a PET strategy’ Chem. Commun., 2021, 57, 13530-13533.
    • J. Kim, S. Lee, S. Kim, M. Jung, H. Lee*, M. S. Han*, ‘Development of a fluorescent chemosensor for chloride ion detection in sweat using Ag+-benzimidazole complexes’ Dyes Pigm., 2020, 108291.

Qihang Ding

Research interest

Fabrication of organic small molecule probes in the NIR-II

Contact
office
Asan sci. 238
E-mail
dingqihang at whu.edu.cn
Publications
  • Q. Li, Q. Ding, Y. Li, X. Zeng, Y. Liu, S. Lu, H. Zhou, X. Wang, J.Wu, X. Meng, Z. Denga and Y. Xiao ‘Novel small-molecule fluorophores for in vivo NIR-IIa and NIR-IIb imaging’ Chemical Communications. doi:10.1039/c9cc09865h
  • Y. Li, Y. Liu, Q. Li, X. Zeng, T. Tian, W.Zhou, Y. Cui, X. Wang, X. Cheng, Q. Ding, X. Wang, J. Wu, H. Deng, Y. Li, X. Meng, Z. Deng, X. Honga, and Y. Xiao ‘Novel NIR-II organic fluorophores for bioimaging beyond 1550 nm’ Chemical Science. doi:10.1039/c9sc06567a
  • H. Zhou, W. Yi, A. Li, B. Wang, Q. Ding, L. Xue, X. Zeng, Y. Feng, Q. Li, T. Wang, Y. Li, X. Cheng, L. Tang, Z. Deng, M. Wu, Y. Xiao, and X. Hong ‘Specific Small‐Molecule NIR‐II Fluorescence Imaging of Osteosarcoma and Lung Metastasis’ Advanced Healthcare Materials. doi:10.1002/adhm.201901224
    • J. Lin, Q. Li, X. Zeng, Z. Chen, Q. Ding, Y. Li, H. Zhou, X. Meng, D. Chen, Z. Deng, X. Hong and Y. Xiao ‘A novel small-molecule near-infrared II fluorescence probe for orthotopic osteosarcoma imaging’ SCIENCE CHINA Chemistry 63, 766 (2020); doi: 10.1007/s11426-019-9685-6

김정륜 (Jungryun Kim)

Research interest

Bioorthogonal Chemistry, Phototherapeutics

Contact
office
Asan Sci. 548B
E-mail
ryunnkim at korea.ac.kr
Publications
  • J. Gong†, Q. Ding†, Y. Shi, M. Li, C. Liu, W. Zeng, J. Kim, S. Shan, W. Zhang, M. Qi*, J. S. Kim*‎, ‘NIR-responsive gold nanomaterials in photothermal antibacterial therapy: From morphological design to multifunctional platforms’ Coord. Chem. Rev. 2024, 526, 216348. Read here
  • J. Kim†, Y. Xu†*, J. H. Lim†, J. Y. Lee*, M. Li*, J. M. Fox*, M. Vendrell*, J. S. Kim*, ‘Bioorthogonal Activation of Deep Red Photoredox Catalysis Inducing Pyroptosis’ J. Am. Chem. Soc. 2024 (in press). Read here
  • K. Dou†, J. Lu†, Y. Xing, R. Wang, M. Won, J. Kim, F. Yu*, J. S. Kim*, ‘Metabolic Acidity/H2O2 Dual-Cascade-Activatable Molecular Imaging Platform toward Metastatic Breast Tumor Malignancy’ Angew. Chem. Int. Ed. 2024, e202419191. Read here
    • Y. Xu†, J. Kim, H. Rha, J. S. Kim*, ‘Oxidative photocatalysis on intracellular on intracellular membranes lights up Photopyro’ Matter 2024, 7, 3253-3255. Read here
    • F. Mehvari†, V. Ramezanzade†, J. An, J. Kim, M. Dinari*, J. S. Kim*‎, ‘Biopolymer-based hydrogels for biomedical applications: bioactivity and wound healing properties’ Coord. Chem. Rev. 2024, 518, 216093. Read here
    • B. Zhu†, X. Xing, J. Kim, H. Rha, C. Liu, Q. Zhang, L. Zeng*, M. Lan*, J. S. Kim*, ‘Endogenous CO imaging in bacterial pneumonia with a NIR fluorescent probe’ Biomaterials 2023, 304, 122419. Read here
    • S. Lee, J. Yoo, G. Bae, R. Thangam, J. Heo, J. Y. Park, H. Choi, C. Kim, J. An, J. Kim, K. R. Mun, S. Shin, K. Zhang, P. Zhao, Y. Kim, N. Kang, S.-B. Han, D. Kim, J. Yoon, M. Kang, J. Kim, L. Yang, S. Karamikamkar, J. Kim, Y. Zhu, A. H. Najafabadi, D.-H. Kim, K.-B. Lee, S. J. Oh, H.-C. Song, W. Y. Jang, L. Bian, Z. Chu, J. S. Kim, Y. S. Zhang, Y. Kim, H. S. Jang*, S. Kim*, H. Kang*, ‘Photonic control of ligand nanospacing in self-assembly regulates stem cell fate’ Bioact. Mater., 2024, 34, 164-180. Read here
    • J. Kim†, P. Jangili†*, J. Kim†, S. Lucia, J. Ryu, R. Prasad, S. Zi, P. Kim*, W. Sun*, J. S. Kim*, ‘Mitochondrial NIR imaging probe mitigating oxidative damage by targeting HDAC6’ Chem. Commun. 2023, 59, 10109-10112. Read here
    • Z. Mao†, H. Rha†, J. Kim†, X. You, F. Zhang*, W. Tao*, J. S. Kim*, ‘THQ-Xanthene: An Emerging Strategy to Create Next-Generation NIRI/II Fluorophores’ Adv. Sci. 2023, 10, 2301177. Read here
    • M. Li†, J. Kim†, H. Rha, S. Son, Y. Xu*, J. L. Sessler*, J. S. Kim*, ‘Photon-Controlled Pyroptosis Activation (PhotoPyro): An Emerging Trigger for Antitumor Immune Response’ J. Am. Chem. Soc. 2023, 145, 6007-6023. Read here
    • L. Yu†, Y. Xu, J. Kim, J. Lee, J. S. Kim*, ‘A rational design of AIE-active fluorophore for the fingerprint optical detection’ Bull. Korean Chem. Soc. 2023, 44, 516-522. Read here
    • M. Li†, J. Kim, Y. Xu, J. S. Kim*, ‘An acid-activatable nanosensitizer library realizes tunable pyroptosis activation in tumors’ Matter 2023, 6, 15-18. Read here
    • J. Shin†, N. Kang†, B. Kim†, H. Hong, L. Yu, J. Kim, H. Kang*, J. S. Kim*, ‘ One-dimensional nanomaterials for cancer therapy and diagnosis’ Chem. Soc. Rev. 2023, 52, 4488. Read here
    • N. Singh†, J. Kim†, J. Kim†, K. Lee†, Z. Zunbul, I. Lee, S. G. Chi*, J. S. Kim*, ‘Covalent organic framework nanomedicines: Biocompatibility for advanced nanocarriers and cancer theranostics applications’ Bioact. Mater. 2023, 21, 358-380. Read here
    • S. Son†, J. Kim†, J. Kim, B. Kim, J. Lee, Y. Kim, M. Li*, H. Kang*, J. S. Kim*, ‘Cancer therapeutics based on diverse energy sources’ Chem. Soc. Rev. 2022, 51, 8201-8215. Read here
    • H. Chu, L. Yang, L. Yu, J. Kim, J. Zhou*, M. Li*, J. S. Kim*, ‘Fluorescent probes in public health and public safety’ Coord. Chem. Rev. 449, 214208, 2021. Read here

나현지 (Hyeonji Rha)

Research interest

Photodynamic Therapy, Photoredox Catalysts

Contact
office
Asan Sci. 238
E-mail
sweethew at korea.ac.kr
Publications
  • Y. Xu, J. Kim, H. Rha, and J. S. Kim, ‘Oxidative photocatalysis on intracellular on intracellular membranes lights up Photopyro’ Matter Previews 2024. Read here
  • Y. Zhang†, S. Wang†, H. Rha†, C. Xu, Y. Pei, X. Ji, J. Zhang, R. Lu, S. Zhang, Z. Xie, and J. S. Kim, ‘Bifunctional black phosphorus quantum dots platform: Delivery and remarkable immunotherapy enhancement of STING agonist’ Biomaterials 2024. Read here
  • B. Zhu, X. Xing, J. Kim, H. Rha, C. Liu, Q. Zhang, L. Zeng, M. Lan, and J. S. Kim, ‘Endogenous CO imaging in bacterial pneumonia with a NIR fluorescent probe’ Biomaterials. 2023. Read here
    • Y. Mao†, M. Lu†, H. Rha†, W. Yang, A. Sharma, Y. Sun, and J. S. Kim, ‘Lighting Up Plants with Near-Infrared Fluorescence Probes’ SCI China Chem 2023. Read here
    • Z. Mao, H. Rha, J. Kim, X. You, F. Zhang, W. Tao, and J. S. Kim, ‘THQ-Xanthene: An Emerging Strategy to Create Next-Generation NIRI/II Fluorophores’ Adv. Sci. 2023, 10, 2301177. Read here
    • M. Li, J. Kim, H. Rha, S. Son, M. S. Levine, Y. Xu, J. L. Sessler, and J. S. Kim, ‘Photon-Controlled Pyroptosis Activation (PhotoPyro): An Emerging Trigger for Antitumor Immune Response’ J. Am. Chem. Soc. 2023, 145, 11, 6007-6023. Read here
    • J. An, H. Hong, M. Won, H. Rha, Q. Ding, N. Kang, H. Kang, J. S. Kim, ‘Mechanical stimuli-driven cancer therapeutics’ Chem. Soc. Rev. 2023 , 52, 30-46. Read here
    • C. Zhang, J. An, J. Wu, W. Liu, H. Rha, J. S. Kim, P. Wang, ‘Structural modification of NIR-II fluorophores for angiography beyond 1300 nm: Expanding the xanthene universe’ Biosens. Bioelectron., 2022, 12, 217, 114701.
    • H. Xiong, Y. Xu, B. Kim, H. Rha, B. Zhang, M. Li, G.-F. Yang, J. S. Kim, ‘Photo-Controllable Biochemistry: Exploiting the Photocages in Phototherapeutic Window.’ Chem 2023, 9, 29-64.DOI: 10.1016/j.chempr.2022.11.007.
    • H. Singh, D. Sareen, J. M. George, V. Bhardwaj, S. H. Rha, S. J. Lee, S. Sharma, A. Sharma, J. S. Kim, ‘Mitochondria-targeted fluorogenic theranostic agents for cancer therapy’ Coord. Chem. Rev., 2022, 12 , 452, 214283.

김은지 (Eunji Kim)

Research interest

Cancer Therapy, Photoredox Catalyst

Contact
office
Asan Sci. 337
E-mail
ksilvergadamas at korea.ac.kr
Publications
  • J. Li, E. Pang. J. An, Z. Xiong, E. Kim, M. Lan, Q.-Y. Cao, J. S. Kim, ‘Off-photosensitizing derived immuno-photodynamic therapy toward postoperative care’ Adv. Funct. Mater., 2025, in press.
  • N. Singh, D. Kim, S. Min, E. Kim, S. Kim, Y. S. Zhang, H. Kang, J. S. Kim, ‘Multimodal synergistic ferroptosis cancer therapy’ Coord. Chem. Rev., 2025, 522, 216236.
  • E. Nestoros, A. Sharma, E. Kim, J. S. Kim, M. Vendrell, ‘Smart Molecular Designs and Applications of Activatable Organic Photosensitizers’ Nat. Rev. Chem., 2025, 1-15.
    • L. Mei, Q. Ding, Y. Xie, H. Liu, H. Li, E. Kim, X. Shen, Y. Zhang, S. Zhang, J. S. Kim, ‘Self-Propelling Intelligent Nanomotor: A Dual-Action Photothermal and Starvation Strategy for Targeted Deep Tumor Destruction’ Biomaterials, 2024, 122968.
    • Y. Yang, M. Ma, L. Shen, J. An, E. Kim, H. Liu, M. Jin, S. Wang, J. Zhang, J. S. Kim, C. Yin, ‘A Fluorescent Probe for Investigating the Role of Biothiols in Signaling Pathways Associated with Cerebral Ischemia-Reperfusion Injury’ Angew. Chem., Int. Ed., 2023, 62, e202310408.
    • J. Kim, S. Lee, Y. Kim, M. Choi, I. Lee, E. Kim, C. G. Yoon, K. Pu, H. Kang, J. S. Kim ‘In situ self-assembly for cancer therapy and imaging’ Nat. Rev. Mater., 2023, 8, 11, 710-725.
    • N. Singh, J. Kim, J. Kim, K. Lee, Z. Zunbul, I. Lee, E. Kim, S. G. Chi, J. S. Kim, ‘Covalent organic framework nanomedicines: Biocompatibility for advanced nanocarriers and cancer theranostics applications’ Bioact. Mater., 2023, 21, 358-380.
    • Z. Longhui, H. Zhang, M. Won, E. Kim, M. Li, J. S. Kim, ‘Codoping g-C3N4 with boron and graphene quantum dots: Enhancement of charge transfer for ultrasensitive and selective photoelectrochemical detection of dopamine’ Biosens. Bioelectron., 2022, 115050.

이기쁨 (Kippeum Lee)

Research interest

Drug delivery system, organic synthesis

Contact
office
Asan Sci. 548B
E-mail
kippeumlee at korea.ac.kr
Publications
  • M. Lee, J. Song, J. Shin, J. Myeong, K. Lee, T. Kim, K. Park and B. K. Oh ‘Horseradish Peroxidase-Encapsulated Fluorescent Bio-Nanoparticle for Ultra-Sensitive and Easy Detection of Hydrogen Peroxide' Biosensors, 2023, 13, 289. Read here

김유진 (Yujin Kim)

Research interest

Cancer stem cell therapy & Drug Delivery System

Contact
office
Asan Sci. 238
E-mail
yujin3495 at korea.ac.kr
Publications
  • J. Gong, X. Wang, J. Wu, C. Yoon, Y. Kim, J. Zou, Z. Mao, J. S. Kim, ‘Diaminonaphthalene Boronic Acid (DANBA): New Approach for Peroxynitrite Sensing Site’ Angew. Chem. Int. Ed., 2024, 67, 35, e202409295. Read here

  • A. Sharma, P. Verwilst, M. Li, D. Ma, N. Singh, J. Yoo, Y. Kim, Y. Yang, J.-H. Zhu, H. Huang, X.-L. Hu, X.-P. He, L. Zeng, T. D. James, X. Peng, J. L. Sessler, J. S. Kim, ‘Theranostic Fluorescent Probes’ Chem. Rev., 2024, 124, 2699-2804. Read here

    • C. Xu, J.-F. Cao, Y. Pei, Y. Kim, H. Moon, C.-Q. Fan, M.-C. Liao, X.-Y. Wang, F. Yao, Y.-J. Zhang, S.-H. Zhang, J. Zhang, J.-Z. Li, J. S. Kim, L. Ma, Z.-J. Xie, J. Control. Release, 2024, 370, 339-353. Read here

유지영 (Jiyoung Yoo)

Research interest

Photodynamic therapy, Drug delivery system

Contact
office
Asan Sci. 337
E-mail
jyoo0263 at gmail.com
Publications
  • Y. Qian†, J. Ding†, R. Zhao, Y. Song, J. Yoo, H. Moon, S. Koo, J. S. Kim, and J. Shen, ‘Intrinsic immunomodulatory hydrogels for chronic inflammation’ Chem. Soc. Rev. 2025, Advanced Article. Read here
  • X. Wang†, W. Chi, J. Wu, J. Zou, J. Yoo, S. Hong, F. Zhang, Z. Mao, and J. S. Kim, ‘A NIR-II emissive sonosensitized biotuner for pyroptosis-enhanced sonodynamic therapy of hypoxic tumors’ Biomaterials 2025, 315, 122969. Read here
    • K. Wang†, Z. Cao†, Q. Ding, J. Yoo, N. Singh, H. Kang, L. Wang, L. Xu, and J. S. Kim, ‘Electronic structure tuning of layered double hydroxides for electrochemical sensing and its biomedical applications’ Sci. China Chem. 2024, 67, 3614-3630. Read here
    • J. Kim†, J. Yoo†, B. Kim†, K.-W. Lee†, S. Kim, S. Hong, J. S. Kim, ‘An AIE-based fluorescent probe to detect peroxynitrite levels in human serum and its cellular imaging’ Chem. Commun. 2024, Advanced Article Read here

    • A. Sharma†, P. Verwilst†, M. Li†, D. Ma†, N. Singh, J. Yoo, Y. Kim, Y. Yang, J.-H. Zhu, H. Huang, X.-L. Hu, X.-P. He, L. Zeng, T. D. James, X. Peng, J. L. Sessler, J. S. Kim, ‘Theranostic Fluorescent Probes’ Chem. Rev. 2024, 124, 2081-2888 Read here

    • N. Singh†, M. Won†, Y. Xu†, C. Yoon, J. Yoo, M. Li, H. Kang, J. S. Kim, ‘Covalent organic framework nanoparticles: Overcoming the challenges of hypoxia in cancer therapy’ Coord. Chem. Rev. 2024, 499, 215481 Read here

윤찬규 (Changyu Yoon)

Research interest

Small-molecular Optical Imaging & Photodynamic therapy

Contact
office
Asan sci. 346
E-mail
cksckstns at korea.ac.kr
Publications
  • J. M. George,J. An, C. Yoon, D. Kim, S. Sharma, A. Sharma, J. S. Kim, ‘Fluorescence Imaging in Drug Delivery Systems’ Imaging Tools for Chemical Biology, 2024. Read here

  • J. Gong, X. Wang, J. Wu, C. Yoon, Y. Kim, J. Zou, Z. Mao, J. S. Kim, ‘Diaminonaphthalene Boronic Acid (DANBA): New Approach for Peroxynitrite Sensing Site’ Angew. Chem. Int. Ed., 2024, 67, 35, e202409295. Read here

  • N. Singh, M. Won, J. An, C. Yoon, D. Kim, S. J. Lee, H. Kang, J. S. Kim, ‘Advances in covalent organic frameworks for cancer phototherapy’ Coord. Chem. Rev., 2024, 506, 215720. Read here

    • N. Singh, M. Won, Y. Xu, C. Yoon, J. Yoo, M. Li, H. Kang, J. S. Kim, ‘Covalent organic framework nanoparticles: Overcoming the challenges of hypoxia in cancer therapy’ Coord. Chem. Rev., 2024, 499, 215481. Read here

    • J. Kim, S. Lee, Y. Kim, M. Choi, I. Lee, E. Kim, C. G. Yoon, K. Pu, H. Kang, J. S. Kim ‘In situ self-assembly for cancer therapy and imaging’ Nat. Rev. Mater., 2023, 8, 710-725. Read here

    • Y. Xu, C. Yoon, J. S. Kim, ‘NIR-II thiopyrylium dyads guided photodynamic inactivation of coronavirus’ Sci China Chem, 2023, 66, 1877–1878. Read here

김고은 (Goeun Kim)

Research interest

Photodynamic therapy, Drug delivery system

Contact
office
Asan Sci. 238
E-mail
oxygen6090 at gmail.com
Publications


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