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안주성 (Jusung An)

Research interest

Small-molecule fluorescence optical imaging

Contact
office
Asan Sci. 346
E-mail
jusung0614 at korea.ac.kr
Publications
  • N. Singh, M. Won, J. An, C. Yoon, D. Kim, S. J. Lee, H. Kang, J. S. Kim, ‘Advances in covalent organic frameworks for cancer phototherapy’ Coord. Chem. Rev. 2024, in press.
  • J. An, K. Kim, H. J. Lim, H. Y. Kim, J. Shin, I. Park, I. Cho, H. Y. Kim, S. Kim, C. McLean, K. Y. Choi, Y. Kim, K. H. Lee, J. S. Kim, ‘Early onset diagnosis in Alzheimer’s disease patients via amyloid-β oligomers-sensing probe in cerebrospinal fluid’ Nat. Commun. 2024, 15, 1004. Read here
  • S. Lee, J. Yoo, G. Bae, R. Thangam, J. Heo, J. Y. Park, H. Choi, C. Kim, J. An, J. Kim, K. R. Mun, S. Shin, K. Zhang, P. Zhao, Y. Kim, N. Kang, S.-B. Han, D. Kim, J. Yoon, M. Kang, J. Kim, L. Yang, S. Karamikamkar, J. Kim, Y. Zhu, A. H. Najafabadi, D.-H. Kim, K.-B. Lee, S. J. Oh, H.-C. Song, W. Y. Jang, L. Bian, Z. Chu, J. S. Kim, Y. S. Zhang, Y. Kim, H. S. Jang, S. Kim, H. Kang, ‘Photonic control of ligand nanospacing in self-assembly regulates stem cell fate’ Bioact. Mater. 2024, 34, 164-180. Read here
    • Y. Yang, M. Ma, L. Shen, J. An, E. Kim, H. Liu, M. Jin, S. Wang, J. Zhang, J. S. Kim, C. Yin, ‘A Fluorescent Probe for Investigating the Role of Biothiols in Signaling Pathways Associated with Cerebral Ischemia-Reperfusion Injury’ Angew. Chem., Int. Ed. 2023, 135, e202310408. Read here
    • H. -W. Kwon, J. An, J. S. Kim, I. -C. Kang, ‘Inhibitory effects of NSAID-conjugated SN-38 on the viability of A549 Non-small cell lung cancer cells’ Biochem. Biophys. Rep. 2023, 35, 101517. Read here
    • M. A. Tekalgne, H. H. Do, T. V. Nguyen, Q. V. Le, J. An, S. H. Hong, S. H. Ahn, H. Kang, J. S. Kim, S. Y. Kim, ‘Efficient Electrocatalysts for Hydrogen Evolution Reaction using Heteroatom-Doped MXene Nanosheet’ Int. J. Energy Res. 2023, 2023, 8980888. Read here
    • J. Shin, J. An, J. Kim, Y. Noh, P. Jangili, J. S. Kim, ‘Ratiometric Fluorescent Chemosensors: Photophysical/Chemical Mechanism Principles and Design Strategies’ Fluorescent Chemosensors 2023, 124-159.
    • Z. Zunbul, J. An, H. Aziz, J. Shin, S. Lim, Y. K. Kim, J. S. Kim, ‘Tailoring hydrophobicity of Thioflavin T to optimize Aβ fibril bioimaging’ Adv. Nanobiomed. Res. 2023, 3, 2200161. Read here
    • Z. Liu, Z. Han, X. Jin, J. An, J. Kim, W. Chen, J. S. Kim, J. Zheng, J. Deng, ‘Regulating the microenvironment with nanomaterials: Potential strategies to ameliorate COVID-19’ Acta Pharm. Sin. B 2023 (in press). Read here
    • J. An, H. Hong, M. Won, H. Rha, Q. Ding, N. Kang, H. Kang, J. S. Kim, ‘Mechanical stimuli-driven cancer therapeutics’ Chem. Soc. Rev. 2023, 52, 30-46. Read here
    • Y. Xu, C. Li, J. An, X. Ma, J. Yang, L. Luo, Y. Deng, J. Kim, Y. Sun, ‘Construction of a 980 nm laser-activated Pt(II) metallacycle nanosystem for efficient and safe photo-induced bacteria sterilization’ Sci. China Chem. 2023, 66, 155-163. Read here
    • C. Zhang, J. An, J. Wu, W. Liu, H. Rha, J. S. Kim, P. Wang, ‘Structural modification of NIR-II fluorophores for angiography beyond 1300 nm: Expanding the xanthene universe’ Biosens. Bioelectron., 2022, 217, 114701. Read here
    • X. He, J.-T. Hou, X. Sun, P. Jangili, J. An, Y. Qian, J. S. Kim, J. Shen ‘NIR-II Photo-Amplified Sonodynamic Therapy Using Sodium Molybdenum Bronze Nanoplatform Against Subcutaneous Staphylococcus Aureus Infection’ Adv. Func. Mat., 2022, 38, 2203964. Read here
    • J. An, P. Verwilst, H. Aziz, J. Shin, S. Lim, I. Kim, Y. K. Kim, J. S. Kim, ‘Picomolar-Sensitive β-Amyloid Fibril Fluorophores by Tailoring the Hydrophobicity of Biannulated π-Elongated Dioxaborine-Dyes’ Bioact. Mater., 2022, 13, 239-248. Read here
    • Y. Xu, Y. Wang, J. An, A. C. Sedgwick, M. Li, J. Xie, W. Hu, J. Kang, S. Sen, A. Steinbrueck, B. Zhang, L. Qiao, S. Wageh, J. F. Arambula, L. Liu, H. Zhang, J. L. Sessler, J. S. Kim, ‘2D-Ultrathin MXene/DOXjade Platform for Iron Chelation Chemo-photothermal Therapy’ Bioact. Mater., 2022, 14, 76-85. Read here

    • Z. Mao, J. Xiong, P. Wang, J. An, F. Zhang, Z. Liu, J. S. Kim, ‘Activity-based Fluorescence Probes for Pathophysiological Peroxynitrite Fluxes’ Coord. Chem. Rev., 2022, 454, 214356. Read here

    • N. Singh, S. Son, J. An, I. Kim, M. Choi, N. Kong, W. Tao, J. S. Kim, ‘Nanoscale porous organic polymers for drug delivery and advanced cancer theranostics’ Chem. Soc. Rev., 2021, 50, 12883-12896. Read here

    • J. An, P. Jangili, S. Lim, Y. K. Kim, P. Verwilst, J. S. Kim ‘Multichromatic Fluorescence towards Aberrant Proteinaceous Aggregates utilizing Benzimidazole-based ICT Fluorophores’ J. Incl. Phenom. Macrocycl. Chem., 2021, 101, 205-215. Read here

    • S. Wang, W. X. Ren, J-T. Hou, M. Won, J. An, X. Chen, J. Shu and J. S. Kim ‘Fluorescence imaging of pathophysiological microenvironments’ Chem. Soc. Rev., 2021, 50, 8887-8902. Read here

    • E. Jung, I. Shim, J. An, M. S. Ji, P. Jangili, S-G. Chi, J. S. Kim ‘Phenylthiourea-conjugated BODIPY as an efficient photosensitizer for tyrosinase-positive melanoma-targeted photodynamic therapy’ ACS Appl. Bio Mater., 2021, 4, 2120-2127. Read here

    • Y. Ren, A. C. Sedgwick, J. Chen, G. Thiabaud, C. V. Chau, J. An, J. F. Arambula, X-P. He, J. S. Kim, J. L. Sessler, C. Liu ‘Manganese(II) Texaphyrin: A Paramagnetic Photoacoustic Contrast Agent Activated by Near-IR Light’ J. Am. Chem. Soc., 2020, 142, 16156-16160. Read here

    • J. Li, Y. Zhang, P. Wang, L. Yu, J. An, G. Deng, Y. Sun, J. S. Kim ‘Reactive Oxygen Species, Thiols and Enzymes Activable AIEgens from Single Fluorescence Imaging to Multifunctional Theranostics’ Coord. Chem. Rev., 2020, 427, 213559. Read here

    • Y. Xu, Y. Zhang, J. Li, J. An, C. Li, S. bai, A. Sharma, G. Deng, J. S. Kim, Y. Sun, ‘NIR-II Emissive Multifunctional AIEgen with Single Laser-Activated Synergistic Photodynamic/Photothermal Therapy of Cancers and Pathogens’ Biomaterials, 2020, 259, 120315. Read here

    • Y.-H. Zhang, X. Li, L. Huang, H. S. Kim, J. An, M. Lan, Q.-Y. Cao, J. S. Kim, ‘AIE based GSH activatable photosensitizer for imaging-guided photodynamic therapy’ Chem. Commun., 2020, 56, 10317-10320. Read here

    • Z. Xie, T. Fan, J. An, W. Choi, Y. Duo, Y. Ge, B. Zhang, G. Nie, N. Xie, H. Zhang, J. S. Kim, ‘Emerging combination strategies with phototherapy in cancer nanomedicine’ Chem. Soc. Rev., 2020, 49, 8065-8087. Read here

    • J. Wu, L. Jiang, P. Verwilst, J. An, H. Zeng, L. Zeng, G. Niu, J. S. Kim ‘A colorimetric and fluorescence lighting-up sensor based on ICT coupled with PET for rapid, specific and sensitive detection of nitrite in food’ Chem. Commun., 2019, 55, 9947-9950. Read here

김재원 (Jaewon Kim)

Research interest

Organic synthesis & Optical imaging probe

Contact
office
Asan Sci. 337
E-mail
kcjb2929 at gmail.com
Publications
  • J. Kim, J. Yoo, B. Kim, K.-W. Lee, S. Kim, S. Hong, J. S. Kim, ‘An AIE-based fluorescent probe to detect peroxynitrite levels in human serum and its cellular imaging’ Chem. Commun., 2024, Advanced Article Read here

  • F. Mehvari, V. Ramezanzade, P. Asadi, N. Singh, J. Kim, M. Dinari*, J. S. Kim* ‘A panoramic perspective of recent progress in 2D and 3D covalent organic frameworks for drug delivery’ Aggregate, 2024, e480.
  • J. Xiong, X. Wang J. Kim, J. Gong, Z. Mao*, J. S. Kim*, Z. Liu* ‘Tumor-Activated Prodrug with Synergistic Anti-Stemness Chemical and Photodynamic Therapies’ Adv. Funct. Mater., 2023, 2312590.
    • J. Kim, S. Lee, Y. Kim, M. Choi, I. Lee, E. Kim, C. G. Yoon, K. Pu*, H. Kang*, J. S. Kim* ‘In situ self-assembly for cancer therapy and imaging’ Nat. Rev. Mater., 2023, 8, 710-725.
    • Z. Liu, Z. Han, X. Jin, J. An, J. Kim, W. Chen, J. S. Kim*, J. Zheng*, J. Deng*, ‘Regulating the microenvironment with nanomaterials: Potential strategies to ameliorate COVID-19’ Acta Pharm. Sin. B., 2023, 13(9), 3638-3658.
    • M. Park, K. Sunwoo, Y.-J. Kim, M. Won, Y. Xu, J. Kim, Z. Pu, M. Li*, J. Y. Kim*, J. H. Seo*, J. S. Kim*, ‘Cutting Off H+ Leaks on Inner Mitochondrial Membrane: A Proton Modulation Approach to Selectively Eradicate Cancer Stem Cells.’ J. Am. Chem. Soc., 2023, 8, 4647-4658.
    • N.Singh, J. Kim, J. Kim, K. Lee, Z. Zunbul, I. Lee, S. G. Chi*, J. S. Kim*, ‘Covalent organic framework nanomedicines: Biocompatibility for advanced nanocarriers and cancer theranostics applications’ Bioact. Mater., 2023, 21, 358-380.
    • S. Son, J. Kim, J. Kim, B. Kim, J. Lee, Y. Kim, M. Li*, H. Kang*, J. S. Kim*, ‘Cancer therapeutics based on diverse energy sources’ Chem. Soc. Rev., 2022, 51, 8201-8215.
    • J. Kim, S. Lee, M. S. Han*, ‘pH-guided fluorescent sensing probe for the discriminative detection of Cl and Br in human serum’ Anal. Chim. Acta, 2022, 1210, 339879.
    • L.-X. Huang, Y.-B. He, J. Kim, A. Sharma, Q.-Y. Cao*, J. S. Kim*, ‘Pyridinium-conjugated polynorbornenes for nanomolar ATP sensing using an indicator displacement assay and a PET strategy’ Chem. Commun., 2021, 57, 13530-13533.
    • J. Kim, S. Lee, S. Kim, M. Jung, H. Lee*, M. S. Han*, ‘Development of a fluorescent chemosensor for chloride ion detection in sweat using Ag+-benzimidazole complexes’ Dyes Pigm., 2020, 108291.

Qihang Ding

Research interest

Fabrication of organic small molecule probes in the NIR-II

Contact
office
Asan sci. 238
E-mail
dingqihang at whu.edu.cn
Publications
  • Q. Li, Q. Ding, Y. Li, X. Zeng, Y. Liu, S. Lu, H. Zhou, X. Wang, J.Wu, X. Meng, Z. Denga and Y. Xiao ‘Novel small-molecule fluorophores for in vivo NIR-IIa and NIR-IIb imaging’ Chemical Communications. doi:10.1039/c9cc09865h
  • Y. Li, Y. Liu, Q. Li, X. Zeng, T. Tian, W.Zhou, Y. Cui, X. Wang, X. Cheng, Q. Ding, X. Wang, J. Wu, H. Deng, Y. Li, X. Meng, Z. Deng, X. Honga, and Y. Xiao ‘Novel NIR-II organic fluorophores for bioimaging beyond 1550 nm’ Chemical Science. doi:10.1039/c9sc06567a
  • H. Zhou, W. Yi, A. Li, B. Wang, Q. Ding, L. Xue, X. Zeng, Y. Feng, Q. Li, T. Wang, Y. Li, X. Cheng, L. Tang, Z. Deng, M. Wu, Y. Xiao, and X. Hong ‘Specific Small‐Molecule NIR‐II Fluorescence Imaging of Osteosarcoma and Lung Metastasis’ Advanced Healthcare Materials. doi:10.1002/adhm.201901224
    • J. Lin, Q. Li, X. Zeng, Z. Chen, Q. Ding, Y. Li, H. Zhou, X. Meng, D. Chen, Z. Deng, X. Hong and Y. Xiao ‘A novel small-molecule near-infrared II fluorescence probe for orthotopic osteosarcoma imaging’ SCIENCE CHINA Chemistry 63, 766 (2020); doi: 10.1007/s11426-019-9685-6

김정륜 (Jungryun Kim)

Research interest

Bioorthogonal Chemistry, Phototherapeutics

Contact
office
Asan Sci. 548B
E-mail
ryunnkim at korea.ac.kr
Publications
  • B. Zhu†, X. Xing, J. Kim, H. Rha, C. Liu, Q. Zhang, L. Zeng, M. Lan, and J. S. Kim, ‘Endogenous CO imaging in bacterial pneumonia with a NIR fluorescent probe’ Biomaterials. 2023. Read here
  • J. Kim†, P. Jangili†, J. Kim†, S. Lucia, J. Ryu, R. Prasad, S. Zi, P. Kim, W. Sun and J. S. Kim, Chem. ‘Mitochondrial NIR imaging probe mitigating oxidative damage by targeting HDAC6’ Chem. Commun., 2023, 59, 10109-10112.
  • Z. Mao†, H. Rha†, J. Kim†, X. You, F. Zhang, W. Tao and J. S. Kim, ‘THQ-Xanthene: An Emerging Strategy to Create Next-Generation NIRI/II Fluorophores’ Adv. Sci. 2023, 10, 2301177
    • M. Li†, J. Kim†, H. Rha, S. Son, Y. Xu, J. L. Sessler and J. S. Kim, ‘Photon-Controlled Pyroptosis Activation (PhotoPyro): An Emerging Trigger for Antitumor Immune Response’ J. Am. Chem. Soc. 2023, 145, 11, 6007-6023.
    • L. Yu†, Y. Xu, J. Kim, J. Lee, J. S. Kim*, ‘A rational design of AIE-active fluorophore for the fingerprint optical detection’ Bull. Korean Chem. Soc., 2023, 1–7.
    • M. Li†, J. Kim, Y. Xu, J. S. Kim*, ‘An acid-activatable nanosensitizer library realizes tunable pyroptosis activation in tumors’ Matter, 2023, 6, 1, 15-18.
    • N.Singh†, J. Kim†, J. Kim†, K. Lee†, Z. Zunbul, I. Lee, S. G. Chi*, J. S. Kim*, ‘Covalent organic framework nanomedicines: Biocompatibility for advanced nanocarriers and cancer theranostics applications’ Bioact. Mater., 2023, 21, 358-380.
    • S. Son†, J. Kim†, J. Kim, B. Kim, J. Lee, Y. Kim, M. Li, H. Kang, J. S. Kim*, ‘Cancer therapeutics based on diverse energy sources’ Chem. Soc. Rev., 2022, 51, 8201-8215.
    • H. Chu, L. Yang, L. Yu, J. Kim, J. Zhou*, M. Li*, J. S. Kim*, ‘Fluorescent probes in public health and public safety’ Coord. Chem. Rev., 214208, 449, 2021.

나현지 (Hyeonji Rha)

Research interest

Photodynamic Therapy, Photoredox Catalysts

Contact
office
Asan Sci. 238
E-mail
sweethew at korea.ac.kr
Publications
  • B. Zhu, X. Xing, J. Kim, H. Rha, C. Liu, Q. Zhang, L. Zeng, M. Lan, and J. S. Kim, ‘Endogenous CO imaging in bacterial pneumonia with a NIR fluorescent probe’ Biomaterials. 2023. Read here
  • Y. Mao†, M. Lu†, H. Rha†, W. Yang, A. Sharma, Y. Sun, and J. S. Kim, ‘Lighting Up Plants with Near-Infrared Fluorescence Probes’ SCI China Chem 2023. Read here
  • Z. Mao, H. Rha, J. Kim, X. You, F. Zhang, W. Tao, and J. S. Kim, ‘THQ-Xanthene: An Emerging Strategy to Create Next-Generation NIRI/II Fluorophores’ Adv. Sci. 2023, 10, 2301177. Read here
    • M. Li, J. Kim, H. Rha, S. Son, M. S. Levine, Y. Xu, J. L. Sessler, and J. S. Kim, ‘Photon-Controlled Pyroptosis Activation (PhotoPyro): An Emerging Trigger for Antitumor Immune Response’ J. Am. Chem. Soc. 2023, 145, 11, 6007-6023. Read here
    • J. An, H. Hong, M. Won, H. Rha, Q. Ding, N. Kang, H. Kang, J. S. Kim, ‘Mechanical stimuli-driven cancer therapeutics’ Chem. Soc. Rev. 2023 (in press). Read here
    • C. Zhang, J. An, J. Wu, W. Liu, H. Rha, J. S. Kim, P. Wang, ‘Structural modification of NIR-II fluorophores for angiography beyond 1300 nm: Expanding the xanthene universe’ Biosens. Bioelectron., 2022, 12, 217, 114701.
    • H. Xiong, Y. Xu, B. Kim, H. Rha, B. Zhang, M. Li, G.-F. Yang, J. S. Kim, ‘Photo-Controllable Biochemistry: Exploiting the Photocages in Phototherapeutic Window.’ Chem 2023, 9, 29-64.DOI: 10.1016/j.chempr.2022.11.007.
    • H. Singh, D. Sareen, J. M. George, V. Bhardwaj, S. H. Rha, S. J. Lee, S. Sharma, A. Sharma, J. S. Kim, ‘Mitochondria-targeted fluorogenic theranostic agents for cancer therapy’ Coord. Chem. Rev., 2022, 12 , 452, 214283.

김은지 (Eunji Kim)

Research interest

Cancer Therapy, Photoredox Catalyst

Contact
office
Asan Sci. 337
E-mail
ksilvergadamas at korea.ac.kr
Publications
  • Y. Yang, M. Ma, L. Shen, J. An, E. Kim, H. Liu, M. Jin, S. Wang, J. Zhang, J. S. Kim, C. Yin, ‘A Fluorescent Probe for Investigating the Role of Biothiols in Signaling Pathways Associated with Cerebral Ischemia-Reperfusion Injury’ Angew. Chem., Int. Ed. 2023, in press.
  • J. Kim, S. Lee, Y. Kim, M. Choi, I. Lee, E. Kim, C. G. Yoon, K. Pu, H. Kang, J. S. Kim ‘In situ self-assembly for cancer therapy and imaging’ Nat. Rev. Mater., 2023, in press.
  • N. Singh, J. Kim, J. Kim, K. Lee, Z. Zunbul, I. Lee, E. Kim, S. G. Chi, J. S. Kim, ‘Covalent organic framework nanomedicines: Biocompatibility for advanced nanocarriers and cancer theranostics applications’ Bioact. Mater., 2023, 21, 358-380.
    • Z. Longhui, H. Zhang, M. Won, E. Kim, M. Li, J. S. Kim, ‘Codoping g-C3N4 with boron and graphene quantum dots: Enhancement of charge transfer for ultrasensitive and selective photoelectrochemical detection of dopamine’ Biosens. Bioelectron., 2022, 115050.

이기쁨 (Kippeum Lee)

Research interest

Drug delivery system, organic synthesis

Contact
office
Asan Sci. 548B
E-mail
kippeumlee at korea.ac.kr
Publications
  • M. Lee, J. Song, J. Shin, J. Myeong, K. Lee, T. Kim, K. Park and B. K. Oh ‘Horseradish Peroxidase-Encapsulated Fluorescent Bio-Nanoparticle for Ultra-Sensitive and Easy Detection of Hydrogen Peroxide' Biosensors, 2023, 13, 289. Read here


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